Double Marker Test- First Trimester
- Category
- Pregnancy
- Sample
- Blood sample taken from a vein in your arm
- Reports () Terms & Conditions Report time varies with time of sample collection.
- In 3 days
- Fasting
- No Fasting
- Age
- 21-45 Years
What Is This Test?
The double marker test measures PAPP-A and free beta-hCG in the mother's blood in the first trimester.
Why this test is performed?
Combined with the nuchal translucency ultrasound, it estimates the risk of chromosomal conditions such as Down syndrome (trisomy 21) and trisomies 18 and 13.
Who should take this test?
Women planning pregnancy or who are pregnant, as advised by the gynaecologist.
Test Preparation
No fasting needed.
What's included 2 parameters
Double Marker (2)
- Free Beta HCG
- PAPP-A (pregnancy-associated plasma protein-A)
Medical disclaimer · for information only, not medical advice
This article is for general information and education only. It is not medical advice, does not create a doctor–patient relationship, and is not a substitute for consultation with a qualified doctor who has assessed your individual situation. Never delay seeking medical advice because of something you have read here.
In a medical emergency, call 112, or 108 for an ambulance where that service operates, or go to your nearest emergency department. If you are in mental health distress, Tele-MANAS is free and available 24×7 on 14416.
Read our Editorial Policy and Medical Review Process.
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Frequently asked questions
Between 11 weeks and 13 weeks 6 days of pregnancy, along with the NT scan.
No. Screening tests estimate risk only. A high-risk result is followed by counselling and, if chosen, confirmatory tests such as NIPT, CVS or amniocentesis.
No fasting is needed. You can eat and drink normally unless your doctor has advised otherwise.
Blood sample taken from a vein in your arm.
Usually within 41–65 hours after the sample reaches the lab. You will receive the report online.
This test is meant for women only.
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