Hemoglobin Variant Analysis Test (HPLC Test)
- Category
- Blood
- Sample
- Blood sample taken from a vein in your arm
- Reports () Terms & Conditions Report time varies with time of sample collection.
- In 3 days
- Fasting
- No Fasting
- Age
- All Ages
What Is This Test?
Separates and measures the different types of haemoglobin in your blood (HbA, HbA2, HbF, HbS and other variants) using HPLC.
Why this test is performed?
The main test to detect thalassaemia trait or major, sickle cell disease and other haemoglobin disorders. Recommended for carrier screening before marriage or pregnancy and to investigate anaemia that does not respond to iron.
Who should take this test?
Tiredness, weakness, pale skin, fever, frequent infections, easy bruising or bleeding; routine health check-ups.
Test Preparation
No fasting needed.
What's included 15 parameters
- RDW-SD
- Haemoglobin A0 (HB A0)
- Haemoglobin D (HbD)
- MCV
- PCV Haematocrit
- Haemoglobin E (HbE)
- MCH
- MCHC
- Hemoglobin Hb
- Haemoglobin A2 (HbA2)
- Haemoglobin S (HbS)
- RBC Count
- RDW-CV
- Foetal Haemoglobin (HbF)
- Haemoglobin C (HbC)
Medical disclaimer · for information only, not medical advice
This article is for general information and education only. It is not medical advice, does not create a doctor–patient relationship, and is not a substitute for consultation with a qualified doctor who has assessed your individual situation. Never delay seeking medical advice because of something you have read here.
In a medical emergency, call 112, or 108 for an ambulance where that service operates, or go to your nearest emergency department. If you are in mental health distress, Tele-MANAS is free and available 24×7 on 14416.
Read our Editorial Policy and Medical Review Process.
- Report time: In 5 days
- No fasting
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Frequently asked questions
There is a 25% chance in each pregnancy that the baby will have thalassaemia major. Genetic counselling and prenatal testing are advised.
No fasting is needed. You can eat and drink normally unless your doctor has advised otherwise.
Blood sample taken from a vein in your arm.
Usually within 29–53 hours after the sample reaches the lab. You will receive the report online.
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