Quadruple Marker Test
- Category
- Pregnancy
- Sample
- Blood sample taken from a vein in your arm
- Reports () Terms & Conditions Report time varies with time of sample collection.
- In 5 days
- Fasting
- No Fasting
- Age
- 21-45 Years
What Is This Test?
The quadruple marker test measures AFP, hCG, unconjugated estriol and inhibin A in the mother's blood in the second trimester.
Why this test is performed?
Estimates the risk of Down syndrome, trisomy 18 and neural tube defects; it is more accurate than the triple marker.
Who should take this test?
Women planning pregnancy or who are pregnant, as advised by the gynaecologist.
Test Preparation
No fasting needed.
What's included 4 parameters
Beta HCG (Total) (1)
- Beta HCG (Total)
Alphafeto Protein (1)
- Alphafeto Protein
uE3, Unconjucated Estriol (1)
- uE3, Unconjucated Estriol
Inhibin A (1)
- Inhibin A
Medical disclaimer · for information only, not medical advice
This article is for general information and education only. It is not medical advice, does not create a doctor–patient relationship, and is not a substitute for consultation with a qualified doctor who has assessed your individual situation. Never delay seeking medical advice because of something you have read here.
In a medical emergency, call 112, or 108 for an ambulance where that service operates, or go to your nearest emergency department. If you are in mental health distress, Tele-MANAS is free and available 24×7 on 14416.
Read our Editorial Policy and Medical Review Process.
- Report time: In 5 days
- No fasting
- Report time: In 3 days
- No fasting
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Frequently asked questions
Usually between 15 and 20 weeks of pregnancy.
No. Screening tests estimate risk only. A high-risk result is followed by counselling and, if chosen, confirmatory tests such as NIPT, CVS or amniocentesis.
No fasting is needed. You can eat and drink normally unless your doctor has advised otherwise.
Blood sample taken from a vein in your arm.
Usually within 3–4 days after the sample reaches the lab. You will receive the report online.
This test is meant for women only.
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