Combined Screening with PlGF- Roche (Astraia) Test
- Category
- Pregnancy
- Sample
- Blood sample taken from a vein in your arm
- Reports () Terms & Conditions Report time varies with time of sample collection.
- In 5 days
- Fasting
- No Fasting
- Age
- 21-45 Years
What Is This Test?
First-trimester combined screening that uses the mother's blood markers (PAPP-A and free beta-hCG), the NT ultrasound scan and maternal factors to estimate the risk of Down syndrome and trisomies 18 and 13, plus pre-eclampsia risk (using PlGF).
Why this test is performed?
Identifies pregnancies at higher risk of chromosomal conditions so that further testing can be offered. Done between 11 and 14 weeks of pregnancy.
Who should take this test?
Women planning pregnancy or who are pregnant, as advised by the gynaecologist.
Test Preparation
No fasting needed.
What's included 2 parameters
Placental Growth Factor (PLGF)- Roche (Astraia) (1)
- Placental Growth Factor (PLGF)- Roche (Astraia)
PAPPa (1)
- PAPPa
Medical disclaimer · for information only, not medical advice
This article is for general information and education only. It is not medical advice, does not create a doctor–patient relationship, and is not a substitute for consultation with a qualified doctor who has assessed your individual situation. Never delay seeking medical advice because of something you have read here.
In a medical emergency, call 112, or 108 for an ambulance where that service operates, or go to your nearest emergency department. If you are in mental health distress, Tele-MANAS is free and available 24×7 on 14416.
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Frequently asked questions
No. Screening tests estimate risk only. High-risk results are followed by counselling and, if chosen, confirmatory tests such as NIPT, CVS or amniocentesis.
No fasting is needed. You can eat and drink normally unless your doctor has advised otherwise.
Blood sample taken from a vein in your arm.
Usually within 3–4 days after the sample reaches the lab. You will receive the report online.
This test is meant for women only.
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